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Study on cytotoxicity of contraceptive materials of scrotiform intrauterine device
Zhong Xingming,Wei Xiangcai,Zhu Guoping,Li Yanqiu,Wu Yuanyuan,Li Zhicai,Guo Jianhua,Zeng Xingrong
Strategic Study of CAE 2015, Volume 17, Issue 6, Pages 8-12
Objective: To evaluate the cytotoxicity of contraceptive materials of scrotiform Intrauterine DeviceMethod: Make a cytotoxicity experiment with the additional liquid silicone rubber newly developed (formulasolution group, positive control solution group, 100% ,50%,25% material extract group’s cell cytotoxicity
Keywords: intrauterind device silicone rubber material cytotoxicity animal experiment ;mouse
Shuai Ma, Huan Zhang, Xiaoyan Dong, Linling Yu, Jie Zheng, Yan Sun
Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 2, Pages 283-295 doi: 10.1007/s11705-017-1687-2
Keywords: Alzheimer’s disease amyloid β-protein cyclic peptide inhibition protein aggregation
Qian-Yuan Wu, Yi-Jun Yan, Yao Lu, Ye Du, Zi-Fan Liang, Hong-Ying Hu
Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 2, doi: 10.1007/s11783-019-1204-6
Keywords: Chlorination Dichloroacetonitrile Aspartic acid Asparagine Toxicity index
Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 10, doi: 10.1007/s11783-023-1725-x
● Effects of AER adsorption and NF on DBP precursors, DBPs, and TOX were examined.
Keywords: Disinfection byproducts Control Anion exchange resin Nanofiltration Cytotoxicity
Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 3, doi: 10.1007/s11783-020-1335-9
•ZnO/Perlite inactivated 72% of bioaerosols in continuous gas phase.
Keywords: Immobilized catalysts Continuous flow Photocatalysis Bioaerosols Cytotoxicity Inactivation mechanism
Jwa-Kyung Kim, Satoshi Uchiyama, Hua Gong, Alexandra Stream, Liangfang Zhang, Victor Nizet
Engineering 2021, Volume 7, Issue 8, Pages 1149-1156 doi: 10.1016/j.eng.2020.09.013
Staphylococcus (S.) aureus is a leading human pathogen capable of producing severe invasive infections such as bacteremia, sepsis, and endocarditis with high morbidity and mortality, exacerbated by the increasingly widespread antibiotic resistance exemplified by methicillin-resistant strains (MRSA). S. aureus pathogenesis is fueled by the secretion of toxins—such as the membrane-damaging pore-forming atoxin,
which have diverse cellular targets including the epithelium, endothelium, leukocytes, and platelets. Here, we examine the use of human platelet membrane-coated nanoparticles (PNPs) as a biomimetic decoy strategy to neutralize S. aureus toxins and preserve host cell defense functions. The PNPs blocked platelet damage induced by S. aureus secreted toxins, thereby supporting platelet activation and bactericidal
activity. Likewise, the PNPs blocked macrophage damage induced by S. aureus secreted toxins, thus supporting macrophage oxidative burst, nitric oxide production, and bactericidal activity, and diminishing MRSA-induced neutrophil extracellular trap release. In a mouse model of MRSA systemic infection, PNP administration reduced bacterial counts in the blood and protected against mortality. Taken together, the results from the present work provide a proof of principle of the therapeutic benefit of PNPs in toxin neutralization, cytoprotection, and increased host resistance to invasive S. aureus infection.
Keywords: Nanoparticle Nanosponge Platelet Staphylococcus aureus Bacterial toxins Sepsis
Title Author Date Type Operation
Study on cytotoxicity of contraceptive materials of scrotiform intrauterine device
Zhong Xingming,Wei Xiangcai,Zhu Guoping,Li Yanqiu,Wu Yuanyuan,Li Zhicai,Guo Jianhua,Zeng Xingrong
Journal Article
Head-to-tail cyclization of a heptapeptide eliminates its cytotoxicity and significantly increases its
Shuai Ma, Huan Zhang, Xiaoyan Dong, Linling Yu, Jie Zheng, Yan Sun
Journal Article
Identification of important precursors and theoretical toxicity evaluation of byproducts driving cytotoxicity
Qian-Yuan Wu, Yi-Jun Yan, Yao Lu, Ye Du, Zi-Fan Liang, Hong-Ying Hu
Journal Article
Control strategies for disinfection byproducts by ion exchange resin, nanofiltration and their sequential combination
Journal Article
Response of bioaerosol cells to photocatalytic inactivation with ZnO and TiO impregnated onto Perlite and Poraver carriers
Journal Article